4of3: Difference between revisions

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==Crystal Structure of SYG-1 D1-D2, Glycosylated==
==Crystal Structure of SYG-1 D1-D2, Glycosylated==
<StructureSection load='4of3' size='340' side='right' caption='[[4of3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4of3' size='340' side='right'caption='[[4of3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4of3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OF3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4of3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OF3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4of0|4of0]], [[4of6|4of6]], [[4of7|4of7]], [[4of8|4of8]], [[4ofd|4ofd]], [[4ofi|4ofi]], [[4ofk|4ofk]], [[4ofp|4ofp]], [[4ofy|4ofy]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4of3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4of3 OCA], [https://pdbe.org/4of3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4of3 RCSB], [https://www.ebi.ac.uk/pdbsum/4of3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4of3 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CELE_K02E10.8, K02E10.8, syg-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4of3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4of3 OCA], [http://pdbe.org/4of3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4of3 RCSB], [http://www.ebi.ac.uk/pdbsum/4of3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4of3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYG1_CAEEL SYG1_CAEEL] Cell adhesion protein (PubMed:15035988). Involved in synapse formation in the HSNL egg-laying motor neuron (PubMed:12628183, PubMed:15035988, PubMed:21858180, PubMed:24485456). Inhibits assembly of the SCF(sel-10) E3 ubiquitin ligase complex at synapses, and protects them from elimination (PubMed:17626846). Also required for F-actin assembly at the synaptic region and for axon branch formation (PubMed:24439377).<ref>PMID:12628183</ref> <ref>PMID:15035988</ref> <ref>PMID:17626846</ref> <ref>PMID:21858180</ref> <ref>PMID:24439377</ref> <ref>PMID:24485456</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Caeel]]
[[Category: Caenorhabditis elegans]]
[[Category: Garcia, K C]]
[[Category: Large Structures]]
[[Category: Ozkan, E]]
[[Category: Garcia KC]]
[[Category: Cell adhesion]]
[[Category: Ozkan E]]
[[Category: Extracellular]]
[[Category: Immunoglobulin superfamily]]
[[Category: Membrane]]
[[Category: N-linked glycosylation]]
[[Category: Protein binding]]
[[Category: Signaling protein]]
[[Category: Synaptogenesis]]
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