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==Crystal structure of orotate phosphoribosyltransferase (OPRTase) from Burkholderia cenocepacia==
==Crystal structure of orotate phosphoribosyltransferase (OPRTase) from Burkholderia cenocepacia==
<StructureSection load='4ohc' size='340' side='right' caption='[[4ohc]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='4ohc' size='340' side='right'caption='[[4ohc]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ohc]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Burcj Burcj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OHC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OHC FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ohc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OHC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3m3h|3m3h]], [[3dez|3dez]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ohc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ohc OCA], [https://pdbe.org/4ohc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ohc RCSB], [https://www.ebi.ac.uk/pdbsum/4ohc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ohc ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrE, BCAL0204 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216591 BURCJ])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ohc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ohc OCA], [http://pdbe.org/4ohc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ohc RCSB], [http://www.ebi.ac.uk/pdbsum/4ohc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ohc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/B4E589_BURCJ B4E589_BURCJ]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).[HAMAP-Rule:MF_01208][SAAS:SAAS004467_004_016272]  
[https://www.uniprot.org/uniprot/B4E589_BURCJ B4E589_BURCJ] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).[HAMAP-Rule:MF_01208][SAAS:SAAS004467_004_016272]
 
==See Also==
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Burcj]]
[[Category: Burkholderia cenocepacia J2315]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Oprt]]
[[Category: Oprtase]]
[[Category: Ssgcid]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4ohc"