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==A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form==
==A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form==
<StructureSection load='4otk' size='340' side='right' caption='[[4otk]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4otk' size='340' side='right'caption='[[4otk]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4otk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OTK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4otk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OTK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv2971, MT3049 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4otk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4otk OCA], [https://pdbe.org/4otk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4otk RCSB], [https://www.ebi.ac.uk/pdbsum/4otk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4otk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4otk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4otk OCA], [http://pdbe.org/4otk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4otk RCSB], [http://www.ebi.ac.uk/pdbsum/4otk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4otk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Y2971_MYCTU Y2971_MYCTU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beddoe, T]]
[[Category: Large Structures]]
[[Category: Shahine, A]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Oxidoreductase]]
[[Category: Beddoe T]]
[[Category: Tim barrel]]
[[Category: Shahine A]]
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