7vro: Difference between revisions

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'''Unreleased structure'''


The entry 7vro is ON HOLD  until 2024-01-26
==crystal structure of BRD2-BD1 in complex with purine derivative==
 
<StructureSection load='7vro' size='340' side='right'caption='[[7vro]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7vro]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VRO FirstGlance]. <br>
Description: crystal structure of BRD2-BD1 in complex with purine derivative
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=37T:THEOBROMINE'>37T</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vro OCA], [https://pdbe.org/7vro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vro RCSB], [https://www.ebi.ac.uk/pdbsum/7vro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vro ProSAT]</span></td></tr>
[[Category: Mathur, S]]
</table>
[[Category: Padmanabhan, B]]
== Function ==
[[Category: Ashok, S]]
[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
[[Category: Deshmukh, P]]
== References ==
[[Category: Arole, A]]
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arole A]]
[[Category: Ashok S]]
[[Category: Deshmukh P]]
[[Category: Mathur S]]
[[Category: Padmanabhan B]]
Retrieved from "https://proteopedia.org/7vro"