8cx3: Difference between revisions

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'''Unreleased structure'''


The entry 8cx3 is ON HOLD  until Paper Publication
==Crystal structure of full-length mesothelin==
 
<StructureSection load='8cx3' size='340' side='right'caption='[[8cx3]], [[Resolution|resolution]] 3.61&Aring;' scene=''>
Authors: Zhan, J., Esser, L., Xia, D.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8cx3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CX3 FirstGlance]. <br>
Description: Crystal structure of full-length mesothelin
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cx3 OCA], [https://pdbe.org/8cx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cx3 RCSB], [https://www.ebi.ac.uk/pdbsum/8cx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cx3 ProSAT]</span></td></tr>
[[Category: Xia, D]]
</table>
[[Category: Esser, L]]
== Disease ==
[[Category: Zhan, J]]
[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.
== Function ==
[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Membrane-anchored forms may play a role in cellular adhesion.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref>  Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Esser L]]
[[Category: Xia D]]
[[Category: Zhan J]]