4p3x: Difference between revisions

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==Structure of the Fe4S4 quinolinate synthase NadA from Thermotoga maritima==
==Structure of the Fe4S4 quinolinate synthase NadA from Thermotoga maritima==
<StructureSection load='4p3x' size='340' side='right' caption='[[4p3x]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4p3x' size='340' side='right'caption='[[4p3x]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4p3x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P3X FirstGlance]. <br>
<table><tr><td colspan='2'>[[4p3x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P3X FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wzu|1wzu]], [[4hhe|4hhe]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p3x OCA], [https://pdbe.org/4p3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p3x RCSB], [https://www.ebi.ac.uk/pdbsum/4p3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p3x ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nadA, TM_1644 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Quinolinate_synthase Quinolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.72 2.5.1.72] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p3x OCA], [http://pdbe.org/4p3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p3x RCSB], [http://www.ebi.ac.uk/pdbsum/4p3x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p3x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NADA_THEMA NADA_THEMA]] Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity).  
[https://www.uniprot.org/uniprot/NADA_THEMA NADA_THEMA] Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Quinolinate synthase]]
[[Category: Large Structures]]
[[Category: Thema]]
[[Category: Thermotoga maritima MSB8]]
[[Category: Amara, P]]
[[Category: Amara P]]
[[Category: Chan, A]]
[[Category: Chan A]]
[[Category: Cherrier, M V]]
[[Category: Cherrier MV]]
[[Category: Choudens, S Ollagnier de]]
[[Category: Darnault C]]
[[Category: Darnault, C]]
[[Category: Fontecilla-Camps JC]]
[[Category: Fontecilla-Camps, J C]]
[[Category: Ollagnier de Choudens S]]
[[Category: Reichmann, D]]
[[Category: Reichmann D]]
[[Category: Catalytic triad]]
[[Category: Holo-protein]]
[[Category: Iron sulfur cluster]]
[[Category: Nad biosynthesis]]
[[Category: Transferase]]