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==Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I==
==Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I==
<StructureSection load='4per' size='340' side='right' caption='[[4per]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
<StructureSection load='4per' size='340' side='right'caption='[[4per]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4per]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PER OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PER FirstGlance]. <br>
<table><tr><td colspan='2'>[[4per]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PER FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4peq|4peq]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4per FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4per OCA], [https://pdbe.org/4per PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4per RCSB], [https://www.ebi.ac.uk/pdbsum/4per PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4per ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNH1, RCJMB04_22k18 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK]), ANG, RNaseA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4per FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4per OCA], [http://pdbe.org/4per PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4per RCSB], [http://www.ebi.ac.uk/pdbsum/4per PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4per ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ANGI_CHICK ANGI_CHICK]] Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity).
[https://www.uniprot.org/uniprot/Q5ZIY8_CHICK Q5ZIY8_CHICK]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4per" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4per" style="background-color:#fffaf0;"></div>
==See Also==
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
*[[Ribonuclease inhibitor|Ribonuclease inhibitor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Gallus gallus]]
[[Category: Bianchetti, C M]]
[[Category: Large Structures]]
[[Category: Fox, B G]]
[[Category: Bianchetti CM]]
[[Category: Lomax, J E]]
[[Category: Fox BG]]
[[Category: Raines, R T]]
[[Category: Lomax JE]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Raines RT]]
[[Category: Leucine-rich repeat]]
[[Category: Protein-protein complex]]
Retrieved from "https://proteopedia.org/4per"