4pis: Difference between revisions

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==Crystal structure of human adenovirus 8 protease in complex with a nitrile inhibitor==
==Crystal structure of human adenovirus 8 protease in complex with a nitrile inhibitor==
<StructureSection load='4pis' size='340' side='right' caption='[[4pis]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4pis' size='340' side='right'caption='[[4pis]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pis]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ade08 Ade08]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PIS FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pis]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_D8 Human adenovirus D8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PIS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FU:N~2~-[(2R)-2-(3,5-DICHLOROPHENYL)-2-(DIMETHYLAMINO)ACETYL]-N-({2-[(Z)-IMINOMETHYL]PYRIMIDIN-4-YL}METHYL)-L-ISOLEUCINAMIDE'>3FU</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FU:N~2~-[(2R)-2-(3,5-DICHLOROPHENYL)-2-(DIMETHYLAMINO)ACETYL]-N-({2-[(Z)-IMINOMETHYL]PYRIMIDIN-4-YL}METHYL)-L-ISOLEUCINAMIDE'>3FU</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pie|4pie]], [[4piq|4piq]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pis OCA], [https://pdbe.org/4pis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pis RCSB], [https://www.ebi.ac.uk/pdbsum/4pis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pis ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31545 ADE08])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pis OCA], [http://pdbe.org/4pis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pis RCSB], [http://www.ebi.ac.uk/pdbsum/4pis PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pis ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B9A5C1_ADE08 B9A5C1_ADE08]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ade08]]
[[Category: Human adenovirus D8]]
[[Category: Altmann, E]]
[[Category: Large Structures]]
[[Category: Bernardi, A]]
[[Category: Altmann E]]
[[Category: Combrink, K]]
[[Category: Bernardi A]]
[[Category: Ellis, D]]
[[Category: Combrink K]]
[[Category: Erbel, P]]
[[Category: Ellis D]]
[[Category: Grosche, P]]
[[Category: Erbel P]]
[[Category: Hughes, N]]
[[Category: Grosche P]]
[[Category: Jarousse, N]]
[[Category: Hughes N]]
[[Category: Melkko, S]]
[[Category: Jarousse N]]
[[Category: Ramage, P]]
[[Category: Mac Sweeney A]]
[[Category: Sirockin, F]]
[[Category: Melkko S]]
[[Category: Sweeney, A Mac]]
[[Category: Ramage P]]
[[Category: Adenain]]
[[Category: Sirockin F]]
[[Category: Cofactor]]
[[Category: Cysteine protease]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Nitrile inhibitor]]
[[Category: Pvic]]