4pmw: Difference between revisions

<table><tr><td colspan='2'>[[4pmw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PMW FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pmw OCA], [https://pdbe.org/4pmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pmw RCSB], [https://www.ebi.ac.uk/pdbsum/4pmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pmw ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/DI3L2_MOUSE DI3L2_MOUSE] 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.<ref>PMID:23594738</ref>  

[[Category: Mus musculus]]

[[Category: Unidentified]]

[[Category: Faehnle CR]]

[[Category: Joshua-Tor L]]

[[Category: Walleshauser J]]