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==Solution Structure of N-terminal Cytosolic Domain of Rhomboid Intramembrane Protease from Escherichia Coli==
==Solution Structure of N-terminal Cytosolic Domain of Rhomboid Intramembrane Protease from Escherichia Coli==
<StructureSection load='2lep' size='340' side='right'caption='[[2lep]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lep' size='340' side='right'caption='[[2lep]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lep]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lep]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEP FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glpG1, ECs4267 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lep OCA], [https://pdbe.org/2lep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lep RCSB], [https://www.ebi.ac.uk/pdbsum/2lep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lep ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Rhomboid_protease Rhomboid protease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.105 3.4.21.105] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lep OCA], [https://pdbe.org/2lep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lep RCSB], [https://www.ebi.ac.uk/pdbsum/2lep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lep ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/C3SPT7_ECOLX C3SPT7_ECOLX]] Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity).[HAMAP-Rule:MF_01594]
[https://www.uniprot.org/uniprot/GLPG_ECOLI GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.<ref>PMID:17099694</ref> <ref>PMID:16216077</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Rhomboid protease]]
[[Category: Ghasriani H]]
[[Category: Ghasriani, H]]
[[Category: Goto NK]]
[[Category: Goto, N K]]
[[Category: Sherratt AR]]
[[Category: Sherratt, A R]]
[[Category: Cell membrane]]
[[Category: Cytosol]]
[[Category: Domain swapping]]
[[Category: Hydrolase]]
[[Category: Membrane protein]]
[[Category: Micelle]]
[[Category: Serine protease]]
Retrieved from "https://proteopedia.org/2lep"