2lpe: Difference between revisions

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==Solution NMR Structure of the KSR1 CA1-CA1a domain==

== Structural highlights ==

<table><tr><td colspan='2'>[[2lpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPE OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=2LPE FirstGlance].

<table><tr><td colspan='2'>[[2lpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPE OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=2LPE FirstGlance].

</td></tr><tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">Ksr, Ksr1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=2lpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpe OCA], [https://pdbe.org/2lpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpe RCSB], [https://www.ebi.ac.uk/pdbsum/2lpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpe ProSAT]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=2lpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpe OCA], [https://pdbe.org/2lpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpe RCSB], [https://www.ebi.ac.uk/pdbsum/2lpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpe ProSAT]</td></tr>

</table>

== Function ==

[[https://www.uniprot.org/uniprot/KSR1_MOUSE KSR1_MOUSE]] Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.

[https://www.uniprot.org/uniprot/KSR1_MOUSE KSR1_MOUSE] Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: ~~Lk3 transgenic mice~~]]

[[Category: Mus musculus]]

[[Category: Koveal, D]]

[[Category: Koveal D]]

[[Category: Page, R]]

[[Category: Page R]]

[[Category: Peti, W]]

[[Category: Peti W]]

~~[[Category: Cc-sam]]~~

~~[[Category: Coiled-coil]]~~

~~[[Category: Sam domain]]~~

~~[[Category: Scaffolding protein]]~~

~~[[Category: Signaling protein~~]]

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 ==Solution NMR Structure of the KSR1 CA1-CA1a domain==
-<StructureSection load='2lpe' size='340' side='right'caption='[[2lpe]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
+<StructureSection load='2lpe' size='340' side='right'caption='[[2lpe]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2lpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LPE FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2lpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LPE FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ksr, Ksr1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpe OCA], [https://pdbe.org/2lpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpe RCSB], [https://www.ebi.ac.uk/pdbsum/2lpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpe ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpe OCA], [https://pdbe.org/2lpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpe RCSB], [https://www.ebi.ac.uk/pdbsum/2lpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpe ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/KSR1_MOUSE KSR1_MOUSE]] Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.
+[https://www.uniprot.org/uniprot/KSR1_MOUSE KSR1_MOUSE] Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.
 __TOC__
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Mus musculus]]
-[[Category: Koveal, D]]
+[[Category: Koveal D]]
-[[Category: Page, R]]
+[[Category: Page R]]
-[[Category: Peti, W]]
+[[Category: Peti W]]
-[[Category: Cc-sam]]
-[[Category: Coiled-coil]]
-[[Category: Sam domain]]
-[[Category: Scaffolding protein]]
-[[Category: Signaling protein]]