4qgh: Difference between revisions

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<StructureSection load='4qgh' size='340' side='right'caption='[[4qgh]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
<StructureSection load='4qgh' size='340' side='right'caption='[[4qgh]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qgh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staar Staar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QGH FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qgh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MRSA252 Staphylococcus aureus subsp. aureus MRSA252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QGH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=32E:2-(3-CHLOROPHENOXY)-3-FLUORO-4-{(1S)-3-METHYL-1-[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]BUTYL}BENZOIC+ACID'>32E</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=32E:2-(3-CHLOROPHENOXY)-3-FLUORO-4-{(1S)-3-METHYL-1-[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]BUTYL}BENZOIC+ACID'>32E</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qg7|4qg7]], [[4qga|4qga]], [[4qgf|4qgf]], [[4qgg|4qgg]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgh OCA], [https://pdbe.org/4qgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qgh RCSB], [https://www.ebi.ac.uk/pdbsum/4qgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgh ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SAR0483, tmk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=282458 STAAR])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgh OCA], [http://pdbe.org/4qgh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qgh RCSB], [http://www.ebi.ac.uk/pdbsum/4qgh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qgh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KTHY_STAAR KTHY_STAAR]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).  
[https://www.uniprot.org/uniprot/KTHY_STAAR KTHY_STAAR] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Thymidylate kinase|Thymidylate kinase]]
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Staar]]
[[Category: Staphylococcus aureus subsp. aureus MRSA252]]
[[Category: DTMP kinase]]
[[Category: Olivier NB]]
[[Category: Olivier, N B]]
[[Category: Soluble]]
[[Category: Thymidine monphosphate]]
[[Category: Transferase-transferase inhibitor]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/4qgh"