4qhu: Difference between revisions

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<StructureSection load='4qhu' size='340' side='right'caption='[[4qhu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4qhu' size='340' side='right'caption='[[4qhu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qhu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QHU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QHU FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qhu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QHU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL17A, CTLA8, IL17 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qhu OCA], [https://pdbe.org/4qhu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qhu RCSB], [https://www.ebi.ac.uk/pdbsum/4qhu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qhu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qhu OCA], [http://pdbe.org/4qhu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qhu RCSB], [http://www.ebi.ac.uk/pdbsum/4qhu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qhu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN]] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.  
[https://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
 
==See Also==
*[[Interleukin 3D structures|Interleukin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gilliland, G L]]
[[Category: Gilliland GL]]
[[Category: Luo, J]]
[[Category: Luo J]]
[[Category: Malia, T]]
[[Category: Malia T]]
[[Category: Obmolova, G]]
[[Category: Obmolova G]]
[[Category: Teplyakov, A]]
[[Category: Teplyakov A]]
[[Category: Antibody-antigen interaction]]
[[Category: Cystine knot]]
[[Category: Cytokine il-17]]
[[Category: Il-17ra]]
[[Category: Il-17rc]]
[[Category: Immune system]]
[[Category: Molecular asymmetry]]
[[Category: Receptor differentiation]]

Revision as of 11:30, 15 February 2023

Crystal Structure of IL-17A/Fab6785 complex

4qhu, resolution 2.20Å

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