8ajr: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 8ajr is ON HOLD until Paper Publication~~

==The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2==

~~Authors: Singh, H.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[8ajr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AJR FirstGlance]. <br>

~~Description:~~ The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ajr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ajr OCA], [https://pdbe.org/8ajr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ajr RCSB], [https://www.ebi.ac.uk/pdbsum/8ajr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ajr ProSAT]</span></td></tr>

[[Category: ~~Unreleased~~ Structures]]

</table>

[[Category: Singh, H]]

== Function ==

[https://www.uniprot.org/uniprot/A0A8C5LDB3_JACJA A0A8C5LDB3_JACJA] Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).[PIRNR:PIRNR038006]

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Singh H]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8ajr is ON HOLD  until Paper Publication
+==The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2==
+<StructureSection load='8ajr' size='340' side='right'caption='[[8ajr]]' scene=''>
-Authors: Singh, H.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8ajr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AJR FirstGlance]. <br>
-Description: The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ajr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ajr OCA], [https://pdbe.org/8ajr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ajr RCSB], [https://www.ebi.ac.uk/pdbsum/8ajr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ajr ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Singh, H]]
+== Function ==
+[https://www.uniprot.org/uniprot/A0A8C5LDB3_JACJA A0A8C5LDB3_JACJA] Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).[PIRNR:PIRNR038006]
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Singh H]]