8hlo: Difference between revisions
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==Crystal structure of ASAP1-SH3 and MICAL1-PRM complex== | |||
<StructureSection load='8hlo' size='340' side='right'caption='[[8hlo]], [[Resolution|resolution]] 1.17Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8hlo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HLO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HLO FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hlo OCA], [https://pdbe.org/8hlo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hlo RCSB], [https://www.ebi.ac.uk/pdbsum/8hlo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hlo ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Niu | [https://www.uniprot.org/uniprot/ASAP1_MOUSE ASAP1_MOUSE] May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. Plays a role in ciliogenesis (By similarity). Posseses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Niu F]] | |||
[[Category: Wei Z]] | |||
[[Category: Yu C]] | |||
Revision as of 12:48, 22 February 2023
Crystal structure of ASAP1-SH3 and MICAL1-PRM complex
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