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==Solution structure of the complex between the Sgt2 homodimerization domain and the Get5 UBL domain==
==Solution structure of the complex between the Sgt2 homodimerization domain and the Get5 UBL domain==
<StructureSection load='2lxc' size='340' side='right'caption='[[2lxc]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2lxc' size='340' side='right'caption='[[2lxc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lxc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LXC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lxc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LXC FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4goc|4goc]], [[2lxa|2lxa]], [[2lxb|2lxb]], [[4god|4god]], [[4goe|4goe]], [[4gof|4gof]]</div></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lxc OCA], [https://pdbe.org/2lxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lxc RCSB], [https://www.ebi.ac.uk/pdbsum/2lxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lxc ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GET5, MDY2, TMA24, YOL111C ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), SGT2, UNF346, YOR007C ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lxc OCA], [https://pdbe.org/2lxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lxc RCSB], [https://www.ebi.ac.uk/pdbsum/2lxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lxc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MDY2_YEAST MDY2_YEAST]] Required for efficient mating. Involved in the production of alpha-factor, the KAR9 and TUB1 location to the shmoo tip and nuclear migration into pheromone-induced shmoos.<ref>PMID:10514570</ref> <ref>PMID:16390866</ref> [[https://www.uniprot.org/uniprot/SGT2_YEAST SGT2_YEAST]] Co-chaperone that binds to the molecular chaperone Hsp70 (SSA1 and SSA2). Regulates Hsp70 ATPase activity (By similarity). Required for recovery from heat shock.<ref>PMID:12482202</ref> 
[https://www.uniprot.org/uniprot/MDY2_YEAST MDY2_YEAST] Required for efficient mating. Involved in the production of alpha-factor, the KAR9 and TUB1 location to the shmoo tip and nuclear migration into pheromone-induced shmoos.<ref>PMID:10514570</ref> <ref>PMID:16390866</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chartron, J W]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Clemons, W M]]
[[Category: Chartron JW]]
[[Category: Vandervelde, D G]]
[[Category: Clemons Jr WM]]
[[Category: Four-helix bundle]]
[[Category: Vandervelde DG]]
[[Category: Get pathway]]
[[Category: Protein binding-protein binding complex]]
[[Category: Protein-protein interaction]]
[[Category: Ubiquitin-like domain]]
Retrieved from "https://proteopedia.org/2lxc"