2ly8: Difference between revisions
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==The budding yeast chaperone Scm3 recognizes the partially unfolded dimer of the centromere-specific Cse4/H4 histone variant== | ==The budding yeast chaperone Scm3 recognizes the partially unfolded dimer of the centromere-specific Cse4/H4 histone variant== | ||
<StructureSection load='2ly8' size='340' side='right'caption='[[2ly8 | <StructureSection load='2ly8' size='340' side='right'caption='[[2ly8]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ly8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2ly8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LY8 FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ly8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ly8 OCA], [https://pdbe.org/2ly8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ly8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ly8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ly8 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ly8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ly8 OCA], [https://pdbe.org/2ly8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ly8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ly8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ly8 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CENPA_YEAST CENPA_YEAST] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Required for functional chromatin architecture at the yeast 2-micron circle partitioning locus and promotes equal plasmid segregation.<ref>PMID:7698647</ref> <ref>PMID:9741625</ref> <ref>PMID:9584087</ref> <ref>PMID:10454560</ref> <ref>PMID:11063678</ref> <ref>PMID:10891506</ref> <ref>PMID:10499801</ref> <ref>PMID:11606525</ref> <ref>PMID:15590827</ref> <ref>PMID:16207811</ref> <ref>PMID:16966420</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bai | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Feng | [[Category: Bai Y]] | ||
[[Category: Ghirlando | [[Category: Feng H]] | ||
[[Category: Hong | [[Category: Ghirlando R]] | ||
[[Category: Zhou | [[Category: Hong J]] | ||
[[Category: Zhou Z]] | |||
