2m09: Difference between revisions
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==Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition== | ==Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition== | ||
<StructureSection load='2m09' size='340' side='right'caption='[[2m09 | <StructureSection load='2m09' size='340' side='right'caption='[[2m09]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2m09]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2m09]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M09 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M09 FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m09 OCA], [https://pdbe.org/2m09 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m09 RCSB], [https://www.ebi.ac.uk/pdbsum/2m09 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m09 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m09 OCA], [https://pdbe.org/2m09 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m09 RCSB], [https://www.ebi.ac.uk/pdbsum/2m09 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m09 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/SF01_HUMAN SF01_HUMAN] Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.<ref>PMID:8752089</ref> <ref>PMID:10449420</ref> <ref>PMID:9660765</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bagdiul | [[Category: Bagdiul I]] | ||
[[Category: Kang | [[Category: Kang H]] | ||
[[Category: Kern | [[Category: Kern T]] | ||
[[Category: Kraemer | [[Category: Kraemer A]] | ||
[[Category: Madl | [[Category: Madl T]] | ||
[[Category: Maeusbacher | [[Category: Maeusbacher N]] | ||
[[Category: Sattler | [[Category: Sattler M]] | ||
[[Category: Sieber | [[Category: Sieber SA]] | ||
[[Category: Zhang | [[Category: Zhang Y]] | ||
[[Category: Zou | [[Category: Zou P]] | ||
