4qqf: Difference between revisions
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==Crystal structure of mitochondrial import inner membrane translocase subunit TIM50== | ==Crystal structure of mitochondrial import inner membrane translocase subunit TIM50== | ||
<StructureSection load='4qqf' size='340' side='right' caption='[[4qqf]], [[Resolution|resolution]] 2.67Å' scene=''> | <StructureSection load='4qqf' size='340' side='right'caption='[[4qqf]], [[Resolution|resolution]] 2.67Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4qqf]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4qqf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QQF FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqf OCA], [https://pdbe.org/4qqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qqf RCSB], [https://www.ebi.ac.uk/pdbsum/4qqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqf ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TIM50_YEAST TIM50_YEAST] Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex. Does not act as a structural subunit of the TIM23 complex but plays a dynamic role in protein import. Has no phosphatase activity.<ref>PMID:12437924</ref> <ref>PMID:12437925</ref> <ref>PMID:14532110</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: | [[Category: Li JZ]] | ||