2mdf: Difference between revisions

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==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==
==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==
<StructureSection load='2mdf' size='340' side='right'caption='[[2mdf]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
<StructureSection load='2mdf' size='340' side='right'caption='[[2mdf]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDF FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SLC9A1, APNH1, NHE1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [https://pdbe.org/2mdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [https://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [https://pdbe.org/2mdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [https://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN]] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref>
[https://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Alves, C]]
[[Category: Alves C]]
[[Category: Fliegel, L]]
[[Category: Fliegel L]]
[[Category: Lee, B L]]
[[Category: Lee BL]]
[[Category: Sykes, B D]]
[[Category: Sykes BD]]
[[Category: Na+/h+ exchanger]]
[[Category: Nhe1]]
[[Category: Proton transport]]
[[Category: Transmembrane]]