2mdk: Difference between revisions
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==NMR Solution Structure of MSP-P56S Domain/VAPB in DPC== | ==NMR Solution Structure of MSP-P56S Domain/VAPB in DPC== | ||
<StructureSection load='2mdk' size='340' side='right'caption='[[2mdk | <StructureSection load='2mdk' size='340' side='right'caption='[[2mdk]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2mdk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2mdk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDK FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdk OCA], [https://pdbe.org/2mdk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdk RCSB], [https://www.ebi.ac.uk/pdbsum/2mdk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdk ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdk OCA], [https://pdbe.org/2mdk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdk RCSB], [https://www.ebi.ac.uk/pdbsum/2mdk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdk ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[https://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN] Adult-onset proximal spinal muscular atrophy, autosomal dominant;Amyotrophic lateral sclerosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN] Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.<ref>PMID:16891305</ref> <ref>PMID:20940299</ref> <ref>PMID:22131369</ref> | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Lim | [[Category: Lim L]] | ||
[[Category: Qin | [[Category: Qin H]] | ||
[[Category: Song | [[Category: Song J]] | ||