4rlk: Difference between revisions

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<StructureSection load='4rlk' size='340' side='right'caption='[[4rlk]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
<StructureSection load='4rlk' size='340' side='right'caption='[[4rlk]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4rlk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Maize Maize]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RLK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RLK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4rlk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RLK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=E91:4-[(E)-(9H-FLUOREN-9-YLIDENEHYDRAZINYLIDENE)METHYL]BENZOIC+ACID'>E91</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=E91:4-[(E)-(9H-FLUOREN-9-YLIDENEHYDRAZINYLIDENE)METHYL]BENZOIC+ACID'>E91</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rll|4rll]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rlk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rlk OCA], [https://pdbe.org/4rlk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rlk RCSB], [https://www.ebi.ac.uk/pdbsum/4rlk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rlk ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ACK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4577 MAIZE])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rlk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rlk OCA], [http://pdbe.org/4rlk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rlk RCSB], [http://www.ebi.ac.uk/pdbsum/4rlk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rlk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE]] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.  
[https://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Maize]]
[[Category: Zea mays]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Boldyreff BS]]
[[Category: Boldyreff, B S]]
[[Category: Guerra B]]
[[Category: Guerra, B]]
[[Category: Issinger OG]]
[[Category: Issinger, O G]]
[[Category: Jensen HH]]
[[Category: Jensen, H H]]
[[Category: Marcussen N]]
[[Category: Marcussen, N]]
[[Category: Miyata Y]]
[[Category: Miyata, Y]]
[[Category: Niefind K]]
[[Category: Niefind, K]]
[[Category: Rasmussen TDL]]
[[Category: Rasmussen, T D.L]]
[[Category: Schnitzler A]]
[[Category: Schnitzler, A]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 07:02, 2 March 2023

Crystal structure of Z. mays CK2alpha in complex with the ATP-competitive inhibitor 4-[(E)-(fluoren-9-ylidenehydrazinylidene)-methyl] benzoate

4rlk, resolution 1.24Å

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