8akl: Difference between revisions
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==Acyl-enzyme complex of meropenem bound to deacylation mutant KPC-2 (E166Q)== | |||
<StructureSection load='8akl' size='340' side='right'caption='[[8akl]], [[Resolution|resolution]] 1.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8akl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AKL FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=O2F:(2S,3R,4R)-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2H-pyrrole-5-carboxylic+acid'>O2F</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8akl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8akl OCA], [https://pdbe.org/8akl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8akl RCSB], [https://www.ebi.ac.uk/pdbsum/8akl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8akl ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Klebsiella pneumoniae]] | |||
[[Category: Large Structures]] | |||
[[Category: Hinchliffe P]] | |||
[[Category: Spencer J]] | |||
[[Category: Tooke CL]] | |||
Revision as of 07:31, 8 March 2023
Acyl-enzyme complex of meropenem bound to deacylation mutant KPC-2 (E166Q)
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