8alz: Difference between revisions
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==Cryo-EM structure of ASCC3 in complex with ASC1== | |||
<StructureSection load='8alz' size='340' side='right'caption='[[8alz]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8alz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ALZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ALZ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8alz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8alz OCA], [https://pdbe.org/8alz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8alz RCSB], [https://www.ebi.ac.uk/pdbsum/8alz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8alz ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/TRIP4_HUMAN TRIP4_HUMAN] Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function (By similarity).<ref>PMID:12077347</ref> | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hilal T]] | |||
[[Category: Jia J]] | |||
[[Category: Loll B]] | |||
[[Category: Wahl MC]] | |||
Revision as of 07:31, 8 March 2023
Cryo-EM structure of ASCC3 in complex with ASC1
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