8hs3: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8hs3 is ~~ON HOLD until Paper Publication~~

==Gi bound orphan GPR20 in ligand-free state==

~~Authors~~: ~~Lin~~, X., ~~Jiang~~, S., Xu, F.

== Structural highlights ==

<table><tr><td colspan='2'>[[8hs3]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HS3 FirstGlance]. <br>

~~Description~~: Gi bound ~~orphan GPR20~~ in ~~ligand-free state~~

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hs3 OCA], [https://pdbe.org/8hs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hs3 RCSB], [https://www.ebi.ac.uk/pdbsum/8hs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hs3 ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

[[Category: ~~Xu, F~~]]

== Function ==

[[Category: Jiang, S]]

[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>

[[Category: Lin, X]]

== References ==

__TOC__

</StructureSection>

[[Category: Escherichia coli]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Jiang S]]

[[Category: Lin X]]

[[Category: Xu F]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8hs3 is ON HOLD  until Paper Publication
+==Gi bound orphan GPR20 in ligand-free state==
+<StructureSection load='8hs3' size='340' side='right'caption='[[8hs3]], [[Resolution|resolution]] 3.14&Aring;' scene=''>
-Authors: Lin, X., Jiang, S., Xu, F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8hs3]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HS3 FirstGlance]. <br>
-Description: Gi bound orphan GPR20 in ligand-free state
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hs3 OCA], [https://pdbe.org/8hs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hs3 RCSB], [https://www.ebi.ac.uk/pdbsum/8hs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hs3 ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Xu, F]]
+== Function ==
-[[Category: Jiang, S]]
+[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
-[[Category: Lin, X]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Escherichia coli]]
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Jiang S]]
+[[Category: Lin X]]
+[[Category: Xu F]]