2mpm: Difference between revisions
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==Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1== | ==Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1== | ||
<StructureSection load='2mpm' size='340' side='right'caption='[[2mpm | <StructureSection load='2mpm' size='340' side='right'caption='[[2mpm]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2mpm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2mpm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MPM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MPM FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TYS:O-SULFO-L-TYROSINE'>TYS</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mpm OCA], [https://pdbe.org/2mpm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mpm RCSB], [https://www.ebi.ac.uk/pdbsum/2mpm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mpm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mpm OCA], [https://pdbe.org/2mpm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mpm RCSB], [https://www.ebi.ac.uk/pdbsum/2mpm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mpm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CCL11_HUMAN CCL11_HUMAN] In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bridgford | [[Category: Bridgford JL]] | ||
[[Category: Canals | [[Category: Canals M]] | ||
[[Category: Christopoulos | [[Category: Christopoulos A]] | ||
[[Category: Clayton | [[Category: Clayton DJ]] | ||
[[Category: Hinds | [[Category: Hinds MG]] | ||
[[Category: Ludeman | [[Category: Ludeman JP]] | ||
[[Category: Millard | [[Category: Millard CJ]] | ||
[[Category: Payne | [[Category: Payne RJ]] | ||
[[Category: Stone | [[Category: Stone MJ]] | ||
Revision as of 08:03, 8 March 2023
Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1
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