7u8y: Difference between revisions

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'''Unreleased structure'''


The entry 7u8y is ON HOLD  until Paper Publication
==TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics==
 
<StructureSection load='7u8y' size='340' side='right'caption='[[7u8y]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
Authors: Hemphill, W.O., Harvey, S.E., Simpson, S.R., Smalley, T.L., Salsbury, F.R., Perrino, F.W., Hollis, T.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7u8y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7U8Y FirstGlance]. <br>
Description: TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZN:ALIZARIN+RED'>AZN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u8y OCA], [https://pdbe.org/7u8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u8y RCSB], [https://www.ebi.ac.uk/pdbsum/7u8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u8y ProSAT]</span></td></tr>
[[Category: Hollis, T]]
</table>
[[Category: Salsbury, F.R]]
== Function ==
[[Category: Simpson, S.R]]
[https://www.uniprot.org/uniprot/TREX1_MOUSE TREX1_MOUSE] Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair.<ref>PMID:10391904</ref> <ref>PMID:11279105</ref>
[[Category: Hemphill, W.O]]
== References ==
[[Category: Smalley, T.L]]
<references/>
[[Category: Harvey, S.E]]
__TOC__
[[Category: Perrino, F.W]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Harvey SE]]
[[Category: Hemphill WO]]
[[Category: Hollis T]]
[[Category: Perrino FW]]
[[Category: Salsbury FR]]
[[Category: Simpson SR]]
[[Category: Smalley TL]]
Retrieved from "https://proteopedia.org/7u8y"