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==Structural Model for the N-terminal Domain of Human Cdc37==
==Structural Model for the N-terminal Domain of Human Cdc37==
<StructureSection load='2nca' size='340' side='right'caption='[[2nca]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2nca' size='340' side='right'caption='[[2nca]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NCA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NCA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NCA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NCA FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2n5x|2n5x]], [[1us7|1us7]], [[2k5b|2k5b]]</div></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nca OCA], [https://pdbe.org/2nca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nca RCSB], [https://www.ebi.ac.uk/pdbsum/2nca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nca ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDC37, CDC37A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nca OCA], [https://pdbe.org/2nca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nca RCSB], [https://www.ebi.ac.uk/pdbsum/2nca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nca ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CDC37_HUMAN CDC37_HUMAN]] Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.<ref>PMID:8666233</ref>
[https://www.uniprot.org/uniprot/CDC37_HUMAN CDC37_HUMAN] Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.<ref>PMID:8666233</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gelis, I]]
[[Category: Gelis I]]
[[Category: Keramisanou, D]]
[[Category: Keramisanou D]]
[[Category: Zhang, Z]]
[[Category: Zhang Z]]
[[Category: Chaperone]]
[[Category: Cochaperone]]
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