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==Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, F42W, Y79A, and F123Y mutant==
==Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, F42W, Y79A, and F123Y mutant==
<StructureSection load='4s02' size='340' side='right' caption='[[4s02]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='4s02' size='340' side='right'caption='[[4s02]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4s02]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrab Pyrab]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S02 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S02 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4s02]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S02 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S02 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BIF:(R)-2-AMINO-3-(4-PHENYLCYCLOHEXYL)PROPANOIC+ACID'>BIF</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BIF:(R)-2-AMINO-3-(4-PHENYLCYCLOHEXYL)PROPANOIC+ACID'>BIF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s02 OCA], [https://pdbe.org/4s02 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s02 RCSB], [https://www.ebi.ac.uk/pdbsum/4s02 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s02 ProSAT]</span></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1y2q|1y2q]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PAB1490, PYRAB13430, thrS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272844 PYRAB])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine--tRNA_ligase Threonine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.3 6.1.1.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s02 OCA], [http://pdbe.org/4s02 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4s02 RCSB], [http://www.ebi.ac.uk/pdbsum/4s02 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4s02 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYT_PYRAB SYT_PYRAB]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4s02" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4s02" style="background-color:#fffaf0;"></div>
==See Also==
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pyrab]]
[[Category: Large Structures]]
[[Category: Threonine--tRNA ligase]]
[[Category: Pyrococcus abyssi GE5]]
[[Category: Baker, D]]
[[Category: Baker D]]
[[Category: Han, G W]]
[[Category: Han GW]]
[[Category: Mills, J H]]
[[Category: Mills JH]]
[[Category: Nasertorabi, F]]
[[Category: Nasertorabi F]]
[[Category: Pearson, A D]]
[[Category: Pearson AD]]
[[Category: Schultz, P G]]
[[Category: Schultz PG]]
[[Category: Song, Y]]
[[Category: Song Y]]
[[Category: Stevens, R C]]
[[Category: Stevens RC]]
[[Category: Beta-alpha-beta fold]]
[[Category: Biphenylalanine and unnatural amino acid]]
[[Category: Editing domain]]
[[Category: Ligase]]
[[Category: Threonine-trna ligase]]
[[Category: Trna-synthetase]]
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