4tk1: Difference between revisions

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<StructureSection load='4tk1' size='340' side='right'caption='[[4tk1]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4tk1' size='340' side='right'caption='[[4tk1]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4tk1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TK1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TK1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4tk1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TK1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TK1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tk2|4tk2]], [[4tk3|4tk3]], [[4tk4|4tk4]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tk1 OCA], [https://pdbe.org/4tk1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tk1 RCSB], [https://www.ebi.ac.uk/pdbsum/4tk1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tk1 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Gphn, Gph ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tk1 OCA], [http://pdbe.org/4tk1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tk1 RCSB], [http://www.ebi.ac.uk/pdbsum/4tk1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tk1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GEPH_RAT GEPH_RAT]] Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:8264797</ref> <ref>PMID:9990024</ref> [[http://www.uniprot.org/uniprot/GBRA3_RAT GBRA3_RAT]] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
[https://www.uniprot.org/uniprot/GEPH_RAT GEPH_RAT] Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:8264797</ref> <ref>PMID:9990024</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[GABA receptor 3D structures|GABA receptor 3D structures]]
*[[Gephyrin|Gephyrin]]
*[[Gephyrin|Gephyrin]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kasaragod, V B]]
[[Category: Rattus norvegicus]]
[[Category: Maric, H M]]
[[Category: Kasaragod VB]]
[[Category: Schindelin, H]]
[[Category: Maric HM]]
[[Category: Biosynthetic protein]]
[[Category: Schindelin H]]
[[Category: Molybdenum co factor biosynthesis]]
[[Category: Neurotransmitter receptor anchoring]]
[[Category: Scaffolding protein]]
[[Category: Structural protein]]
Retrieved from "https://proteopedia.org/4tk1"