4tlf: Difference between revisions

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<StructureSection load='4tlf' size='340' side='right'caption='[[4tlf]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
<StructureSection load='4tlf' size='340' side='right'caption='[[4tlf]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4tlf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4TLF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4tlf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TLF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA2602, NC002516.2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlf OCA], [https://pdbe.org/4tlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tlf RCSB], [https://www.ebi.ac.uk/pdbsum/4tlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tlf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4tlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlf OCA], [http://pdbe.org/4tlf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tlf RCSB], [http://www.ebi.ac.uk/pdbsum/4tlf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tlf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/3MDO_PSEAE 3MDO_PSEAE] Thiol dioxygenase that catalyzes the dioxygenation of 3-mercaptopropionate (3-MPA) to 3-sulfinopropionate (3-SPA). To a lesser extent (40-fold lower efficiency), is also able to oxidize cysteine to cysteine sulfinate (CSA). Cannot use N-acetyl-L-cysteine, homocysteine, and cysteamine as substrates. The physiological role of this enzyme is unclear.<ref>PMID:26272617</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pseae]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Fellner, M]]
[[Category: Fellner M]]
[[Category: Jameson, G N.L]]
[[Category: Jameson GNL]]
[[Category: Tchesnokov, E P]]
[[Category: Tchesnokov EP]]
[[Category: Wilbanks, S M]]
[[Category: Wilbanks SM]]
[[Category: 3-mpa dioxygenase]]
[[Category: Cupin]]
[[Category: Cysteine dioxygenase]]
[[Category: Non-heme mono-iron]]
[[Category: Oxidoreductase]]
[[Category: Thiol dioxygenase]]