Sandbox Reserved 1790: Difference between revisions

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== Signaling Pathway ==
== Signaling Pathway ==


[[Image:Signal_cascade.jpg|380 px|thumb|center|'''Figure 1:'''Comparison of Delta-opioid receptor to human free-fatty acid receptor (hGPR40) both of which are G-protein coupled receptors. The binding pocket of the delta-opioid receptor is solvent exposed allowing ligands to enter directly from the extracellular space while the binding pocket of hGPR40 is covered by the extracellular loop 2 (ECL2) preventing entry from the extracellular space (ECL2 represented in cyan). The Delta-opioid displays the canonical binding site typical of most GPCRs while ligands of hGPR40 bind to a noncanonical pocket represented in pink.]]
[[Image:Signal_cascade_small.jpg|380 px|thumb|center|'''Figure 1:'''Signaling cascade is shown with SHOC2 in pink, PP1C in blue, and MRAs in white. ]]
 


[[Image:Dephosphorylation.jpg|380 px|thumb|center|'''Figure 2:'''PP1C dephosphorylates RAF protein at serine 259 ]]




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== References ==
== References ==
<references/>
<references/>
<ref name=”Hauseman”>PMID:35830882</ref>.
<ref name=”Kwon”>PMID:35831509</ref>.
<ref name=”Lavoie”>PMID:35970881</ref>.
<ref name=”Liau”>PMID:35768504</ref>.
==Proteopedia Resources==
==Proteopedia Resources==
[http://proteopedia.org/wiki/index.php/Category:Lysophosphatidic_acid_binding Category:Lysophosphatidic acid binding]
[http://proteopedia.org/wiki/index.php/Category:Lysophosphatidic_acid_binding Category:Lysophosphatidic acid binding]
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