Sandbox Reserved 1792: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Grace Lane (talk | contribs) No edit summary |
Grace Lane (talk | contribs) No edit summary |
||
| Line 11: | Line 11: | ||
== Structure== | == Structure== | ||
<scene name='95/952720/Structure_overview/2'>TSHR | <scene name='95/952720/Structure_overview/2'>TSHR has 3 main domains</scene>: Leucine Rich Region Domain (coral), the hinge region (blue-purple), and the transmembrane region. The (rainbow). The leucine rich region domain is located on the outside of the cell. This is where TSH will bind. The hinge region is also extracellular. Conformational changes in this region are responsible for the switch between the [[active vs inactive state]]. | ||
=== Transmembrane Region=== | === Transmembrane Region=== | ||
<scene name='95/952720/Transmembrane_region/1'>Transmembrane Region</scene> (<scene name='95/952720/Transmembrane_region_top-view/1'>top-view</scene>) | <scene name='95/952720/Transmembrane_region/1'>Transmembrane Region</scene> (<scene name='95/952720/Transmembrane_region_top-view/1'>top-view</scene>) | ||
| Line 18: | Line 18: | ||
<scene name='95/952720/Hinge_region/1'>Hinge Region</scene> | <scene name='95/952720/Hinge_region/1'>Hinge Region</scene> | ||
=== Leucine Rich Domain=== | === Leucine Rich Domain=== | ||
<scene name='95/952720/Lrrd/1'>LRRD</scene> | |||
=== Binding Pocket=== | === Binding Pocket=== | ||
