7z5k: Difference between revisions

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'''Unreleased structure'''


The entry 7z5k is ON HOLD  until Paper Publication
==Transcription factor MYF5 bound to non-symmetrical site==
 
<StructureSection load='7z5k' size='340' side='right'caption='[[7z5k]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
Authors: Morgunova, E., Popov, A., Yin, Y., Taipale, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7z5k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z5K FirstGlance]. <br>
Description: Transcription factor MYF5 bound to non-symmetrical site
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z5k OCA], [https://pdbe.org/7z5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z5k RCSB], [https://www.ebi.ac.uk/pdbsum/7z5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z5k ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Popov, A]]
== Disease ==
[[Category: Yin, Y]]
[https://www.uniprot.org/uniprot/MYF5_HUMAN MYF5_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
[[Category: Taipale, J]]
== Function ==
[[Category: Morgunova, E]]
[https://www.uniprot.org/uniprot/MYF5_HUMAN MYF5_HUMAN] Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:29887215). Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.<ref>PMID:2721498</ref> <ref>PMID:29887215</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Morgunova E]]
[[Category: Popov A]]
[[Category: Taipale J]]
[[Category: Yin Y]]

Revision as of 07:18, 22 March 2023

Transcription factor MYF5 bound to non-symmetrical site

7z5k, resolution 2.28Å

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