8g8e: Difference between revisions
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==Human Oct4 bound to nucleosome with human LIN28B sequence== | |||
<StructureSection load='8g8e' size='340' side='right'caption='[[8g8e]], [[Resolution|resolution]] 4.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8g8e]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G8E FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g8e OCA], [https://pdbe.org/8g8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g8e RCSB], [https://www.ebi.ac.uk/pdbsum/8g8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g8e ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PO5F1_HUMAN PO5F1_HUMAN] Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.<ref>PMID:18035408</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Bilokapic S]] | |||
[[Category: Du Y]] | |||
[[Category: Halic M]] | |||
[[Category: Malik D]] | |||
[[Category: Sinha KK]] | |||
Revision as of 07:27, 22 March 2023
Human Oct4 bound to nucleosome with human LIN28B sequence
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