8gyx: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8gyx is ~~ON HOLD until Paper Publication~~

==Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1)==

~~Authors~~: ~~Qian~~, H.W., ~~Wang~~, Z.H.

== Structural highlights ==

<table><tr><td colspan='2'>[[8gyx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GYX FirstGlance]. <br>

~~Description~~: ~~Structural basis for catalysis~~ of ~~human~~ choline/~~ethanolamine phosphotransferase (CEPT1)~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gyx OCA], [https://pdbe.org/8gyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gyx RCSB], [https://www.ebi.ac.uk/pdbsum/8gyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gyx ProSAT]</span></td></tr>

[[Category: ~~Wang, Z.H~~]]

</table>

[[Category: ~~Qian, H.W~~]]

== Function ==

[https://www.uniprot.org/uniprot/CEPT1_HUMAN CEPT1_HUMAN] Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.<ref>PMID:10191259</ref> <ref>PMID:10893425</ref> <ref>PMID:12216837</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Qian HW]]

[[Category: Wang ZH]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8gyx is ON HOLD  until Paper Publication
+==Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1)==
+<StructureSection load='8gyx' size='340' side='right'caption='[[8gyx]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
-Authors: Qian, H.W., Wang, Z.H.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8gyx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GYX FirstGlance]. <br>
-Description: Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gyx OCA], [https://pdbe.org/8gyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gyx RCSB], [https://www.ebi.ac.uk/pdbsum/8gyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gyx ProSAT]</span></td></tr>
-[[Category: Wang, Z.H]]
+</table>
-[[Category: Qian, H.W]]
+== Function ==
+[https://www.uniprot.org/uniprot/CEPT1_HUMAN CEPT1_HUMAN] Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.<ref>PMID:10191259</ref> <ref>PMID:10893425</ref> <ref>PMID:12216837</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Qian HW]]
+[[Category: Wang ZH]]