4u4p: Difference between revisions

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<StructureSection load='4u4p' size='340' side='right'caption='[[4u4p]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
<StructureSection load='4u4p' size='340' side='right'caption='[[4u4p]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4u4p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U4P FirstGlance]. <br>
<table><tr><td colspan='2'>[[4u4p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U4P FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMC2, CAPE, SMC2L1, PRO0324 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), SMC4, CAPC, SMC4L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u4p OCA], [https://pdbe.org/4u4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u4p RCSB], [https://www.ebi.ac.uk/pdbsum/4u4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u4p ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u4p OCA], [http://pdbe.org/4u4p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u4p RCSB], [http://www.ebi.ac.uk/pdbsum/4u4p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u4p ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SMC2_HUMAN SMC2_HUMAN]] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.<ref>PMID:11136719</ref> [[http://www.uniprot.org/uniprot/SMC4_HUMAN SMC4_HUMAN]] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.<ref>PMID:11136719</ref> 
[https://www.uniprot.org/uniprot/SMC2_HUMAN SMC2_HUMAN] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.<ref>PMID:11136719</ref>  
 
==See Also==
*[[Condensin|Condensin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Fukakusa, S]]
[[Category: Fukakusa S]]
[[Category: Fukui, K]]
[[Category: Fukui K]]
[[Category: Hosokawa, Y]]
[[Category: Hosokawa Y]]
[[Category: Kawahara, K]]
[[Category: Kawahara K]]
[[Category: Kobayashi, Y]]
[[Category: Kobayashi Y]]
[[Category: Maruno, T]]
[[Category: Maruno T]]
[[Category: Miyahara, Y]]
[[Category: Miyahara Y]]
[[Category: Nakamura, S]]
[[Category: Nakamura S]]
[[Category: Noda, M]]
[[Category: Noda M]]
[[Category: Ohkubo, T]]
[[Category: Ohkubo T]]
[[Category: Oki, H]]
[[Category: Oki H]]
[[Category: Takino, R]]
[[Category: Takino R]]
[[Category: Uchiyama, S]]
[[Category: Uchiyama S]]
[[Category: Condensin]]
[[Category: Protein binding]]
[[Category: Smc]]

Revision as of 08:02, 22 March 2023

Crystal structure of the human condensin SMC hinge domain heterodimer with short coiled coils

4u4p, resolution 1.89Å

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