Sandbox Reserved 1778: Difference between revisions
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=== SHOC2 === | === SHOC2 === | ||
SHOC2 is a domain which acts as a cradle to bind PP1C and MRAS. The | SHOC2 is a domain which acts as a cradle to bind PP1C and MRAS. The | ||
<scene name='95/952706/Shoc2_structure/ | <scene name='95/952706/Shoc2_structure/7'>structure of SHOC2</scene> | ||
is a leucine rich repeat (LRR) protein that consists of 20 consecutive | is a leucine rich repeat (LRR) protein that consists of 20 consecutive | ||
<scene name='95/952706/Shoc2_structure/6'>LRR regions</scene> | <scene name='95/952706/Shoc2_structure/6'>LRR regions</scene> | ||
. This motif results in an extended beta sheet on the inner concavity of the protein surface with alpha helices facing outward. This results in a largely hydrophobic core. | . This motif results in an extended beta sheet on the inner concavity of the protein surface with alpha helices facing outward. This results in a largely hydrophobic core. | ||
protein phosphatase 1 catalytic subunit ( <scene name='95/952706/Pp1c_structure/ | protein phosphatase 1 catalytic subunit ( <scene name='95/952706/Pp1c_structure/3'>PP1C</scene> ) is highly characterized of serine/ threonine phosphatase. PP1C | ||
<scene name='95/952706/Shoc2_pp1c_interaction/2'>associates</scene>> | <scene name='95/952706/Shoc2_pp1c_interaction/2'>associates</scene>> | ||
associates with the ascending loops of the SHOC2 LRR regions. | associates with the ascending loops of the SHOC2 LRR regions. | ||
