4v2b: Difference between revisions
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<StructureSection load='4v2b' size='340' side='right'caption='[[4v2b]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4v2b' size='340' side='right'caption='[[4v2b]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4v2b]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4v2b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V2B FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v2b OCA], [https://pdbe.org/4v2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v2b RCSB], [https://www.ebi.ac.uk/pdbsum/4v2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v2b ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/UNC5D_RAT UNC5D_RAT] Receptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity).[UniProtKB:Q6UXZ4][UniProtKB:Q8K1S2] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Acker-Palmer | [[Category: Acker-Palmer A]] | ||
[[Category: Border | [[Category: Border EC]] | ||
[[Category: Cop | [[Category: Cop F]] | ||
[[Category: Haertl | [[Category: Haertl R]] | ||
[[Category: Harlos | [[Category: Harlos K]] | ||
[[Category: Jones | [[Category: Jones EY]] | ||
[[Category: Klein | [[Category: Klein R]] | ||
[[Category: Nagel | [[Category: Nagel D]] | ||
[[Category: Ruff | [[Category: Ruff T]] | ||
[[Category: Seiradake | [[Category: Seiradake E]] | ||
[[Category: Seyit-Bremer | [[Category: Seyit-Bremer G]] | ||
[[Category: Toro | [[Category: Del Toro D]] | ||