4whw: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 3: Line 3:
<StructureSection load='4whw' size='340' side='right'caption='[[4whw]], [[Resolution|resolution]] 1.34&Aring;' scene=''>
<StructureSection load='4whw' size='340' side='right'caption='[[4whw]], [[Resolution|resolution]] 1.34&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4whw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WHW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WHW FirstGlance]. <br>
<table><tr><td colspan='2'>[[4whw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WHW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3OT:2-METHOXY-4-{1-[2-(MORPHOLIN-4-YL)ETHYL]-2-(2-PHENYLETHYL)-1H-BENZIMIDAZOL-5-YL}CYCLOHEPTA-2,4,6-TRIEN-1-ONE'>3OT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3OT:2-METHOXY-4-{1-[2-(MORPHOLIN-4-YL)ETHYL]-2-(2-PHENYLETHYL)-1H-BENZIMIDAZOL-5-YL}CYCLOHEPTA-2,4,6-TRIEN-1-ONE'>3OT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4whw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4whw OCA], [http://pdbe.org/4whw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4whw RCSB], [http://www.ebi.ac.uk/pdbsum/4whw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4whw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4whw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4whw OCA], [https://pdbe.org/4whw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4whw RCSB], [https://www.ebi.ac.uk/pdbsum/4whw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4whw ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>  
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).  
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).


==See Also==
==See Also==
Line 18: Line 18:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Basak, A]]
[[Category: Basak A]]
[[Category: Bonin, P D]]
[[Category: Bonin PD]]
[[Category: Chekler, E L.Piatnitski]]
[[Category: Denny RA]]
[[Category: Denny, R A]]
[[Category: Flick AC]]
[[Category: Flick, A C]]
[[Category: Geoghegan KF]]
[[Category: Geoghegan, K F]]
[[Category: Hett EC]]
[[Category: Hett, E C]]
[[Category: Jones LH]]
[[Category: Jones, L H]]
[[Category: Liu S]]
[[Category: Liu, S]]
[[Category: Piatnitski Chekler EL]]
[[Category: Pletcher, M T]]
[[Category: Pletcher MT]]
[[Category: Robinson, R P]]
[[Category: Robinson RP]]
[[Category: Sahasrabudhe, P]]
[[Category: Sahasrabudhe P]]
[[Category: Salter, S]]
[[Category: Salter S]]
[[Category: Stock, I A]]
[[Category: Stock IA]]
[[Category: Brd4]]
[[Category: Bromo domain]]
[[Category: Inhibitor]]
[[Category: Transcription-transcription inhibitor complex]]