4wol: Difference between revisions

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<StructureSection load='4wol' size='340' side='right'caption='[[4wol]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
<StructureSection load='4wol' size='340' side='right'caption='[[4wol]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4wol]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WOL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WOL FirstGlance]. <br>
<table><tr><td colspan='2'>[[4wol]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WOL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wo1|4wo1]], [[2l34|2l34]], [[2l35|2l35]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wol OCA], [https://pdbe.org/4wol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wol RCSB], [https://www.ebi.ac.uk/pdbsum/4wol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wol ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TYROBP, DAP12, KARAP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wol OCA], [http://pdbe.org/4wol PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wol RCSB], [http://www.ebi.ac.uk/pdbsum/4wol PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wol ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/TYOBP_HUMAN TYOBP_HUMAN]] Nasu-Hakola disease. The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/TYOBP_HUMAN TYOBP_HUMAN] Nasu-Hakola disease. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TYOBP_HUMAN TYOBP_HUMAN]] Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.  
[https://www.uniprot.org/uniprot/TYOBP_HUMAN TYOBP_HUMAN] Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Call, M E]]
[[Category: Call ME]]
[[Category: Call, M J]]
[[Category: Call MJ]]
[[Category: Knoblich, K]]
[[Category: Knoblich K]]
[[Category: Alpha-helix transmembrane signalling]]
[[Category: Signaling protein]]
Retrieved from "https://proteopedia.org/4wol"