Sandbox Reserved 1779: Difference between revisions
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[https://www.niddk.nih.gov/health-information/endocrine-diseases/graves-disease Grave's Disease] is an autoimmune disease that is a result of hyperthyroidism, where too much TSH is being produced. The binding of <scene name='95/952708/Tsh_7t9i/1'>TSH</scene> to <scene name='95/952709/Initial_scene_with_edited_7utz/2'>TSHR</scene> results in the receptor remaining in its active conformation. This is important as the thyroid gland controls metabolism in the body and overstimulation can lead to many side effects. This is including but not limited to: eye and skin problems, weight loss, fatigue, muscle weakness, trouble tolerating heat/ profuse sweating, enlarged thyroid glands (goiter). This disease effects 1 in 100 Americans and especially women or people older than 30 years of age. | [https://www.niddk.nih.gov/health-information/endocrine-diseases/graves-disease Grave's Disease] is an autoimmune disease that is a result of hyperthyroidism, where too much TSH is being produced. The binding of <scene name='95/952708/Tsh_7t9i/1'>TSH</scene> to <scene name='95/952709/Initial_scene_with_edited_7utz/2'>TSHR</scene> results in the receptor remaining in its active conformation. This is important as the thyroid gland controls metabolism in the body and overstimulation can lead to many side effects. This is including but not limited to: eye and skin problems, weight loss, fatigue, muscle weakness, trouble tolerating heat/ profuse sweating, enlarged thyroid glands (goiter). This disease effects 1 in 100 Americans and especially women or people older than 30 years of age. | ||
[https://www.mayoclinic.org/ | [https://www.mayoclinic.org/diseasesconditions/hypothyroidism/symptomscauses/syc20350284#:~:text=Hypothyroidism%20happens%20when%20the%20thyroid,symptoms%20in%20its%20early%20stages Hypothyroidism] is the converse of Grave’s Disease as not enough TSH is produced. The most common cause of Hypothyroidism is Hashimoto’s disease. Without enough TSH to bind TSHR, the pathway remains inactive and thus metabolic processes are inhibited in this pathway. This results in many symptoms including, but not limited to fatigue, cold sensitivity, weight gain, irregular/heavy menstrual cycle, thinning of hair, and depression. This disease effects women and those older than the age of 60, but can also occur in infancy. | ||
== Structure == | == Structure == | ||