7ss6: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 7ss6 is ~~ON HOLD until Paper Publication~~

==Structure of Klebsiella LpxH in complex with JH-LPH-45==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7ss6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SS6 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BKB:5-{4-[3-chloro-5-(trifluoromethyl)phenyl]piperazine-1-sulfonyl}-N-[5-(hydroxyamino)-5-oxopentyl]-2,3-dihydro-1H-indole-1-carboxamide'>BKB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ss6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ss6 OCA], [https://pdbe.org/7ss6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ss6 RCSB], [https://www.ebi.ac.uk/pdbsum/7ss6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ss6 ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/A0A1S0WIC1_KLEPN A0A1S0WIC1_KLEPN] Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.[HAMAP-Rule:MF_00575][SAAS:SAAS00911811]

__TOC__

</StructureSection>

[[Category: Klebsiella pneumoniae]]

[[Category: Large Structures]]

[[Category: Cho J]]

[[Category: Cochrane CS]]

[[Category: Zhou P]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7ss6 is ON HOLD  until Paper Publication
+==Structure of Klebsiella LpxH in complex with JH-LPH-45==
+<StructureSection load='7ss6' size='340' side='right'caption='[[7ss6]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7ss6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SS6 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BKB:5-{4-[3-chloro-5-(trifluoromethyl)phenyl]piperazine-1-sulfonyl}-N-[5-(hydroxyamino)-5-oxopentyl]-2,3-dihydro-1H-indole-1-carboxamide'>BKB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ss6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ss6 OCA], [https://pdbe.org/7ss6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ss6 RCSB], [https://www.ebi.ac.uk/pdbsum/7ss6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ss6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A0A1S0WIC1_KLEPN A0A1S0WIC1_KLEPN] Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.[HAMAP-Rule:MF_00575][SAAS:SAAS00911811]
+__TOC__
+</StructureSection>
+[[Category: Klebsiella pneumoniae]]
+[[Category: Large Structures]]
+[[Category: Cho J]]
+[[Category: Cochrane CS]]
+[[Category: Zhou P]]