7xad: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal strucutre of PD-L1 and DBL2_02 designed protein binder== | |||
<StructureSection load='7xad' size='340' side='right'caption='[[7xad]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7xad]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Chemical_production_metagenome Chemical production metagenome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XAD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XAD FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xad FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xad OCA], [https://pdbe.org/7xad PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xad RCSB], [https://www.ebi.ac.uk/pdbsum/7xad PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xad ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chemical production metagenome]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chai Y]] | |||
[[Category: Gao GF]] | |||
[[Category: Han P]] | |||
[[Category: Liu KF]] | |||
[[Category: Pacesa M]] | |||
[[Category: Tan SG]] | |||
[[Category: Xu ZP]] | |||
Revision as of 20:27, 12 April 2023
Crystal strucutre of PD-L1 and DBL2_02 designed protein binder
| ||||||||||||
