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==Solution structure of the chromodomain of Swi6==
==Solution structure of the chromodomain of Swi6==
<StructureSection load='2rso' size='340' side='right'caption='[[2rso]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2rso' size='340' side='right'caption='[[2rso]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rso]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RSO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rso]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RSO FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2rsn|2rsn]]</div></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rso OCA], [https://pdbe.org/2rso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rso RCSB], [https://www.ebi.ac.uk/pdbsum/2rso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rso ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">swi6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rso OCA], [https://pdbe.org/2rso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rso RCSB], [https://www.ebi.ac.uk/pdbsum/2rso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rso ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/SWI6_SCHPO SWI6_SCHPO]] Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Involved in the repression of the silent mating-type loci MAT2 and MAT3. May compact MAT2/3 into a heterochromatin-like conformation which represses the transcription of these silent cassettes.  
[https://www.uniprot.org/uniprot/SWI6_SCHPO SWI6_SCHPO] Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Involved in the repression of the silent mating-type loci MAT2 and MAT3. May compact MAT2/3 into a heterochromatin-like conformation which represses the transcription of these silent cassettes.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fission yeast]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Nishimura, Y]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Shimojo, H]]
[[Category: Nishimura Y]]
[[Category: Chromatin]]
[[Category: Shimojo H]]
[[Category: Chromodomain]]
[[Category: Chromosomal protein]]
[[Category: Methylation]]
[[Category: Silencing]]
[[Category: Transcription]]
Retrieved from "https://proteopedia.org/2rso"