2rt9: Difference between revisions

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==Solution structure of a regulatory domain of meiosis inhibitor==
==Solution structure of a regulatory domain of meiosis inhibitor==
<StructureSection load='2rt9' size='340' side='right'caption='[[2rt9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2rt9' size='340' side='right'caption='[[2rt9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rt9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RT9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rt9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RT9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Fbxo43 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rt9 OCA], [https://pdbe.org/2rt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rt9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rt9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rt9 OCA], [https://pdbe.org/2rt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rt9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rt9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/FBX43_MOUSE FBX43_MOUSE]] Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.  
[https://www.uniprot.org/uniprot/FBX43_MOUSE FBX43_MOUSE] Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Akasaka, R]]
[[Category: Akasaka R]]
[[Category: He, F]]
[[Category: He F]]
[[Category: Ikeda, M]]
[[Category: Ikeda M]]
[[Category: Muto, Y]]
[[Category: Muto Y]]
[[Category: Ohsawa, N]]
[[Category: Ohsawa N]]
[[Category: Shirouzu, M]]
[[Category: Shirouzu M]]
[[Category: Shoji, S]]
[[Category: Shoji S]]
[[Category: Terada, T]]
[[Category: Terada T]]
[[Category: Tsuda, K]]
[[Category: Tsuda K]]
[[Category: Wakiyama, M]]
[[Category: Wakiyama M]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Metal binding protein]]
[[Category: Zinc-finger domain]]
Retrieved from "https://proteopedia.org/2rt9"