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==Solution structures of the DNA-binding domain (ZF6) of immune-related zinc-finger protein ZFAT==
==Solution structures of the DNA-binding domain (ZF6) of immune-related zinc-finger protein ZFAT==
<StructureSection load='2rux' size='340' side='right'caption='[[2rux]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2rux' size='340' side='right'caption='[[2rux]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rux]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RUX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RUX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rux]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RUX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RUX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2elv|2elv]], [[2rut|2rut]], [[2ruu|2ruu]], [[2ruv|2ruv]], [[2ruw|2ruw]], [[2ruy|2ruy]], [[2ruz|2ruz]], [[2rv0|2rv0]], [[2rv1|2rv1]], [[2rv2|2rv2]], [[2rv3|2rv3]], [[2rv4|2rv4]], [[2rv5|2rv5]], [[2rv6|2rv6]], [[2rv7|2rv7]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZFAT, KIAA1485, ZFAT1, ZNF406 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rux OCA], [https://pdbe.org/2rux PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rux RCSB], [https://www.ebi.ac.uk/pdbsum/2rux PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rux ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rux OCA], [https://pdbe.org/2rux PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rux RCSB], [https://www.ebi.ac.uk/pdbsum/2rux PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rux ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN]] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).  
[https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kigawa, T]]
[[Category: Kigawa T]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Umehara, T]]
[[Category: Umehara T]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Transcription]]
[[Category: Zfat]]
[[Category: Zinc finger]]
Retrieved from "https://proteopedia.org/2rux"