4wyv: Difference between revisions

<table><tr><td colspan='2'>[[4wyv]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4jhf 4jhf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WYV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WYV FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wyv OCA], [https://pdbe.org/4wyv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wyv RCSB], [https://www.ebi.ac.uk/pdbsum/4wyv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wyv ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/TSN_HUMAN TSN_HUMAN] DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref>  Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref>  

[[Category: Homo sapiens]]

[[Category: Alian A]]

[[Category: Dvir H]]

[[Category: Eliahoo E]]