Sandbox Reserved 1769: Difference between revisions

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** Formed by transmembrane helices TM1, TM5, and TM6.

*Core domain: <scene name='95/952697/Ntcp_open-pore_state/24'>TM helices 2-4, 7-9</scene>

**Formed by the packing of a helix bundle of TM2, TM3, and TM4 with another helix bundle of TM7, TM8, and TM9 (Figure 3). These <scene name='95/952697/Ntcp_open-pore_state/35'>two helix bundles</scene> are related by pseudo two-fold symmetry.<Ref name="Qi"> Qi X, Li W. Unlocking the secrets to human NTCP structure. Innovation (Camb). 2022 Aug 1;3(5):100294. [https://dx.doi.org/10.1016/j.xinn.2022.100294 DOI: 10.1016/j.xinn.2022.100294]. </Ref>

**Formed by the packing of a helix bundle of TM2, TM3, and TM4 with another helix bundle of TM7, TM8, and TM9 (Figure 3). These <scene name='95/952697/Ntcp_open-pore_state/41'>two helix bundles</scene> are related by pseudo two-fold symmetry.<Ref name="Qi"> Qi X, Li W. Unlocking the secrets to human NTCP structure. Innovation (Camb). 2022 Aug 1;3(5):100294. [https://dx.doi.org/10.1016/j.xinn.2022.100294 DOI: 10.1016/j.xinn.2022.100294]. </Ref>

=== Proline/Glycine Hinge ===

Sandbox Reserved 1769: Difference between revisions

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@@ Line 15: / Line 15: @@
 ** Formed by transmembrane helices TM1, TM5, and TM6.
 *<b><font color="#0040e0">Core domain</font></b>: <scene name='95/952697/Ntcp_open-pore_state/24'>TM helices 2-4, 7-9</scene>
-**Formed by the packing of a helix bundle of <b><font color="blue">TM2, TM3, and TM4</font></b> with another helix bundle of <b><font color="skyblue">TM7, TM8, and TM9</font></b> (Figure 3). These <scene name='95/952697/Ntcp_open-pore_state/35'>two helix bundles</scene> are related by pseudo two-fold symmetry.<Ref name="Qi"> Qi X, Li W. Unlocking the secrets to human NTCP structure. Innovation (Camb). 2022 Aug 1;3(5):100294. [https://dx.doi.org/10.1016/j.xinn.2022.100294 DOI: 10.1016/j.xinn.2022.100294]. </Ref>
+**Formed by the packing of a helix bundle of <b><font color="blue">TM2, TM3, and TM4</font></b> with another helix bundle of <b><font color="skyblue">TM7, TM8, and TM9</font></b> (Figure 3). These <scene name='95/952697/Ntcp_open-pore_state/41'>two helix bundles</scene> are related by pseudo two-fold symmetry.<Ref name="Qi"> Qi X, Li W. Unlocking the secrets to human NTCP structure. Innovation (Camb). 2022 Aug 1;3(5):100294. [https://dx.doi.org/10.1016/j.xinn.2022.100294 DOI: 10.1016/j.xinn.2022.100294]. </Ref>
 === Proline/Glycine Hinge ===