Sandbox Reserved 1783: Difference between revisions

Line 41:

=== Bile Salt Uptake ===

[https://www.niddk.nih.gov/health-information/liver-disease/cirrhosis/definition-facts Cirrhosis], commonly known as the last stage of liver disease, is due to a deficiency in the bile acid supply in the liver. Bile acid pools, as defined by Vlahcevic, are the negatively-charged precursors to bile and often are conjugated to positively-charged bile salts. This is attributed either a decrease in the production of bile salts or a large increase in the excretion of this molecule out of the cell. <Ref name="Cirrhosis"> Vlahcevic, Z., Buhac, I., et al. Bile Acid Metabolism in Patients with Cirrhosis. Gastroenterology vol. 60, 491-498 (1971). [https://www.gastrojournal.org/article/S0016-5085(71)80053-7/fulltext DOI: 10.1016/S0016-5085(71)80053-7]. </Ref> Cirrhosis causes symptoms such as jaundice, abdominal pain and swelling, and swelling of the legs and feet. A patient who has type two diabetes, ~~those4~~ who are biological men, and those who have done or do abuse alcohol are also more susceptible to developing Cirrhosis. This diagnosis can lead to liver failure and other life-threatening diseases, making bile salt uptake essential to liver function.

[https://www.niddk.nih.gov/health-information/liver-disease/cirrhosis/definition-facts Cirrhosis], commonly known as the last stage of liver disease, is due to a deficiency in the bile acid supply in the liver. Bile acid pools, as defined by Vlahcevic, are the negatively-charged precursors to bile and often are conjugated to positively-charged bile salts. This is attributed either a decrease in the production of bile salts or a large increase in the excretion of this molecule out of the cell. <Ref name="Cirrhosis"> Vlahcevic, Z., Buhac, I., et al. Bile Acid Metabolism in Patients with Cirrhosis. Gastroenterology vol. 60, 491-498 (1971). [https://www.gastrojournal.org/article/S0016-5085(71)80053-7/fulltext DOI: 10.1016/S0016-5085(71)80053-7]. </Ref> Cirrhosis causes symptoms such as jaundice, abdominal pain and swelling, and swelling of the legs and feet. A patient who has type two diabetes, those who are biological men, and those who have done or do abuse alcohol are also more susceptible to developing Cirrhosis. This diagnosis can lead to liver failure and other life-threatening diseases, making bile salt uptake essential to liver function.

Sandbox Reserved 1783: Difference between revisions

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

Revision as of 21:04, 16 April 2023 view source Olivia Simcox (talk \| contribs) 68 edits No edit summary ← Older edit		Revision as of 21:05, 16 April 2023 view source Olivia Simcox (talk \| contribs) 68 edits No edit summary Newer edit →
Line 41:		Line 41:
	=== Bile Salt Uptake ===		=== Bile Salt Uptake ===

	[https://www.niddk.nih.gov/health-information/liver-disease/cirrhosis/definition-facts Cirrhosis], commonly known as the last stage of liver disease, is due to a deficiency in the bile acid supply in the liver. Bile acid pools, as defined by Vlahcevic, are the negatively-charged precursors to bile and often are conjugated to positively-charged bile salts. This is attributed either a decrease in the production of bile salts or a large increase in the excretion of this molecule out of the cell. <Ref name="Cirrhosis"> Vlahcevic, Z., Buhac, I., et al. Bile Acid Metabolism in Patients with Cirrhosis. Gastroenterology vol. 60, 491-498 (1971). [https://www.gastrojournal.org/article/S0016-5085(71)80053-7/fulltext DOI: 10.1016/S0016-5085(71)80053-7]. </Ref> Cirrhosis causes symptoms such as jaundice, abdominal pain and swelling, and swelling of the legs and feet. A patient who has type two diabetes, ~~those4~~ who are biological men, and those who have done or do abuse alcohol are also more susceptible to developing Cirrhosis. This diagnosis can lead to liver failure and other life-threatening diseases, making bile salt uptake essential to liver function.		[https://www.niddk.nih.gov/health-information/liver-disease/cirrhosis/definition-facts Cirrhosis], commonly known as the last stage of liver disease, is due to a deficiency in the bile acid supply in the liver. Bile acid pools, as defined by Vlahcevic, are the negatively-charged precursors to bile and often are conjugated to positively-charged bile salts. This is attributed either a decrease in the production of bile salts or a large increase in the excretion of this molecule out of the cell. <Ref name="Cirrhosis"> Vlahcevic, Z., Buhac, I., et al. Bile Acid Metabolism in Patients with Cirrhosis. Gastroenterology vol. 60, 491-498 (1971). [https://www.gastrojournal.org/article/S0016-5085(71)80053-7/fulltext DOI: 10.1016/S0016-5085(71)80053-7]. </Ref> Cirrhosis causes symptoms such as jaundice, abdominal pain and swelling, and swelling of the legs and feet. A patient who has type two diabetes, those who are biological men, and those who have done or do abuse alcohol are also more susceptible to developing Cirrhosis. This diagnosis can lead to liver failure and other life-threatening diseases, making bile salt uptake essential to liver function.